新质生产力在湖北 | 国际领先！光谷“人造血小板”生成率提升至90%
<p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; text-wrap-mode: wrap; background-color: rgb(255, 255, 255);">血液是生命的源泉。在武汉光谷，一项有望终结“血小板荒”的前沿技术正加速走向应用。我国首个“人造血小板”项目，将生成率从10%一举提升到90%，达到国际领先水平。<br style="box-sizing: border-box; -webkit-tap-highlight-color: transparent;"/></p><p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; text-wrap-mode: wrap; background-color: rgb(255, 255, 255);">在华中科技大学同济医院实验室内，一排微流控生物反应器正在运转，透过显微镜可看到血小板正在“生长”。传统血小板全靠志愿者捐献，临床常年紧缺。相关部门预测，到2035年，全国血小板缺口将达250万升。为了解决这一难题，华中科技大学同济医院团队另辟蹊径，模拟人体血管环境，在体外“人造”血小板。</p><p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; text-wrap-mode: wrap; background-color: rgb(255, 255, 255);"><strong style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; font-weight: bold;">湖北创衍生物科技有限公司“芯”血工厂项目负责人 邵利华：</strong>我们使用的原材料其实是人的细胞，人诱导的多能干细胞，这个多能干细胞能够进一步分化成为造血组细胞，进一步分化成为巨核细胞，放在我们造的微流控生物反应器上面，就能够生产出满足临床需求的血小板。</p><p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; text-wrap-mode: wrap; background-color: rgb(255, 255, 255);">这项技术的核心突破，是团队将血管内的“湍流”与“剪切力”双重因素结合到生物反应器中，模拟出最真实的人体血管环境。现在，国际上普遍的血小板生成率只有10%，而这一创新可以让血小板的生成率跃升至90%。</p><p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; text-wrap-mode: wrap; background-color: rgb(255, 255, 255);"><strong style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; font-weight: bold;">湖北创衍生物科技有限公司“芯”血工厂项目负责人 邵利华：</strong>日本和美国处于临床阶段，最长的应该做了大概一二十年。我们研发历程两年左右，在国内属于领先水平。</p><p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; text-wrap-mode: wrap; background-color: rgb(255, 255, 255);">更令人振奋的是，常规血小板只能保存5天，团队研发的冻干技术有望延长至15天。目前，该项目已完成实验室全流程验证，并申请国家发明专利。</p><p style="box-sizing: border-box; -webkit-tap-highlight-color: transparent; margin-top: 1em; margin-bottom: 1em; padding: 0px; word-break: break-word; text-align: justify; text-indent: 2em; font-size: 18px; line-height: 2; color: rgb(51, 51, 51); font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, Helvetica, Segoe UI, Arial, Roboto, PingFang SC, miui, Hiragino Sans GB, Microsoft Yahei, sans-serif; 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